About
Dr. F. Alex Feltus received a BSc in Biochemistry from Auburn University, served two years in the U.S. Peace Corps in the Fiji Islands, and then completed advanced biomedical training at Vanderbilt (PhD) and Emory (postdoc). He has performed research in artificial intelligence, bioinformatics, cyberinfrastructure, high-performance & cloud computing, systems biology, tumor genomics, medical genetics, crop genetics, genome assembly, systems genetics, and paleogenomics. Feltus has published numerous scientific articles in peer-reviewed journals, released open-source software, completed multiple NSF grants, and trained thousands of HS, BS, MS and PhD students in bioinformatics, biochemistry, genetics, biomedical data science, and computer engineering. Currently, Feltus is Professor in Clemson University’s Dept. of Genetics & Biochemistry and CSO/co-founder of Praxis AI LLC.
View Dr. Feltus' Faculty Profile.
How their research is transforming health care
The Feltus lab and collaborators use computational biology techniques to discover biomarker systems that underly complex traits including cancer, autism, and non-ketotic hyperglycinemia. We then hypothesize biochemical mechanisms that drive normal tissue development and how some human tissue shifts to an aberrant state. To do this work, we have developed cloud based compute and storage systems and adapt or develop novel artificial intelligence/machine learning algorithms to detect genetic patterns associated with specific biological conditions.
News and media related to Dr. Feltus’ research
- Study implicates Neanderthal DNA in autism susceptibility: https://news.clemson.edu/study-implicates-neanderthal-dna-in-autism-susceptibility/
- Research faculty launch high-performance computing user group:
https://news.clemson.edu/research-faculty-launch-high-performance-computing-user-group/ - Research on how legumes make their own fertilizer from the air leads to international database
https://news.clemson.edu/research-on-how-legumes-make-their-own-fertilizer-from-the-air-leads-to-international-database/ - Clemson University researchers help personalized medicine take a step forward: https://news.clemson.edu/clemson-university-researchers-help-personalized-medicine-take-a-step-forward/
- Identification of gene networks involved in uterine cancer could lead to better treatment options:
https://news.clemson.edu/identification-of-gene-networks-involved-in-uterine-cancer-could-lead-to-better-treatment-options/ - Clemson grad student focuses on identifying biomarkers in normally functioning brains
https://news.clemson.edu/clemson-grad-student-focuses-on-identifying-biomarkers-in-normally-functioning-brains/ - CENIC - "Big Data: How the PRP Enables Scientists to Unlock Genetic Secrets"
- Louisiana Tech University - "Clemson professor to deliver December New Frontiers seminar"
- Clemson University Newsstand - "Clemson scientists recieve $2.95M to improve and simplify large-scale data analysis"
- Clemson University Newsstand - "Researchers get $1.4 million to sdvance 'big data' for genomic research"
Health Research Expertise Keywords
Cancer biology, machine learning, artificial intelligence, computational biology, autism spectrum disorder, systems biology, cyberinfrastructure
