About
Dr. Emily Rosowski received her BS in Biology at the University of North Carolina at Chapel Hill. Her interests in host-pathogen interactions began in Jeroen Saeij’s lab at Massachusetts Institute of Technology where she received her PhD. Emily performed postdoctoral research in Anna Huttenlocher’s lab at the University of Wisconsin-Madison. She started her own laboratory at Clemson University in 2019 where she is currently an Assistant Professor. The Rosowski lab investigates innate immune responses to pathogens using larval zebrafish as a host model. Currently, her lab focuses on the genetic pathways that macrophages and neutrophils use to control infections with the pathogenic fungus Aspergillus fumigatus.
Visit Dr. Rosowski's Faculty Profile.
How their research is transforming health care
Dr. Rosowski's research is aimed at understanding susceptibility to infectious disease. Many pathogens, including the fungal pathogen Aspergillus fumigatus which is the major focus of her current research, only cause disease in patients with suppressed or dysregulated immune systems. Her research aims to both better understand the cellular and molecular causes of susceptibility in these patients to inform their treatment with current anti-fungal therapies and to develop a better understanding of how healthy immune systems combat pathogens to inform the development of new host-directed therapies that boost immune responses. To do this research, Dr. Rosowski's research team uses an innovative larval zebrafish host model that recapitulates human infectious disease, allows them to genetically interrogate host immune pathways, and in which they can use confocal microscopy to image host and pathogen dynamics in live, infected animals.
Health Research Expertise Keywords
Faculty Scholar, macrophages; neutrophils; fungi; anti-microbial drugs; immunosuppressive drugs; host-directed therapy
