Profile
Laura Finzi
Physics and Astronomy
Endowed Chair-Med Biophysics
APS Fellow
Adjunct Professor of Physics, Emory University
864-656-2296
Jordan Hall G13 [Lab]
Jordan Hall G13A [Research Laboratory Service]
Jordan Hall G14 [Office]
Educational Background
Ph.D., Chemistry, University of New Mexico
B.S., Ind. Chemistry, Universita' di Bologna, Italy
Selected Publications
Jin Qian, Bing Wang, Irina Artsimovitch, David Dunlap, Laura Finzi “Force and the ?-C-terminal domains bias RNA polymerase recycling”, (2024) Nature Comm. 10.1038/s41467-024-51603-3
Jin Qian, Allison Cartee, Wenxuan Xu, Yan Yan, Bing Wang, Irina Artsimovitch, David Dunlap, Laura Finzi “Reciprocating RNA Polymerase batters through roadblocks” (2024) Nature Comm., doi:10.1038/s41467-024-47531-x.
Yue Lu, Gustavo Borjas, Cristine Hendrickson, Zsuzsanna Vörös, David Dunlap, Keith Shearwin and Laura Finzi, “Proteins mediating different DNA topologies block RNAP elongation with different efficiency.” FEBS Letters, 2022, 596, 1994-2006; doi:10.1002/1873-3468.14447. Editor’s choice-Journal cover.
Wenxuan Xu, Yan Yan, Irina Artsimovich, David Dunlap and Laura Finzi, “Positive supercoiling favors transcription elongation through lac repressor-mediated DNA loops”, Nucleic Acids Research 50, 2826-2835, 2022.
Yan Yan, Wenxuan Xu, Sandip Kumar, Alexander Zhang, Fenfei Leng, David D. Dunlap and Laura Finzi, “Negative DNA supercoiling makes protein-mediated looping deterministic and ergodic within the bacterial doubling time”, Nucleic Acids Research 2021, 49(20) 11550-11559; https://doi.org/10.1093/nar/gkab946.
Domenico Salerno, Francesco Mantegazza, Valeria Cassina, Matteo Cristofalo, Qing Shao, Laura Finzi, David Dunlap, “Nanomechanics of negatively supercoiled diaminopurine-substituted DNA”, Nucleic Acids Research, Volume 49, Issue 20, Pages 11778–11786, 18 November 2021; PubMed PMID: 34718727.
Joe Piccolo, Josh Mendez Harper, Wenxuan Xu, Daniel Kovari, David Dunlap, Laura Finzi, “Force spectroscopy with electromagnetic tweezers”, Journal of Applied Physics 130, 134702 (2021). Featured in SciLight: https://doi.org/10.1063/10.0006622; DOI: 10.1063/10.0006622
Daniel T. Kovari, David D. Dunlap, Eric Weeks and Laura Finzi, “Model-free 3D localization with precision estimates for bright field imaged particles” Optics Express, 27(21), 29875-29895, 2019.
Memberships
Biophysical Society, American Physical Society, American Chemical Society
Honors and Awards
APS Fellow
