Using this Guide
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IACUC Resources
General
Responsibilities of the IACUC include oversight of the animal care and use program and its components at Clemson University as described by the agencies and policies outlined below:
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Public Health Service Policy on Humane Care and Use of Laboratory Animals
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Guide for the Care and Use of Agricultural Animals in Research and Teaching (4th Edition) (PDF)
All animal activities must be conducted in accordance with the PHS Policy on the Care and Use of Laboratory Animals, in accordance with the CU PHS Assurance Number D16-00435 (A3737-01) (continued full accreditation) and in accordance with AAALAC International standards (continued full accreditation issued July 08, 2024).
Flyers
Policies
IACUC Function
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1.1 Alternate IACUC Members (PDF)
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1.2 Calling for Full Committee Review (FCR) (PDF)
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1.3 Designated Member Review (DMR) Subsequent to Full Committee Review (FCR) (PDF)
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1.4 Addressing the Departure or Sudden Absence of a Principal Investigator (PDF)
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1.6 Reporting and Investigating Unexpected Outcomes or Adverse Events (PDF)
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1.7 Addressing Non-Compliance with IACUC Policies or Procedures (PDF)
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1.8 Conducting IACUC Business in the Event of an Emergency or Pandemic (PDF)
Protocol Creation and Review
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2.1 Guidelines on Which Activities Require an Animal Use Protocol (PDF)
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2.2 Training Requirements (PDF)
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2.3 Non-Clemson University Personnel Participating in Activities Covered by an AUP (PDF)
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2.4 Literature Searches (PDF)
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2.5 Approved Numbers for Faunal Surveys and Breeding Colonies (PDF)
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2.6 Changes to Animal Activities Previously Approved by the IACUC (Amendments to AUPs) (PDF)
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2.8 Requirements for Flowcharts (PDF)
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2.9 Veterinary Verification and Consultation (VVC) Review (PDF)
General Animal Use
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3.2 The Reuse of Research Animals (PDF)
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3.3 Food and Fluid Restriction (PDF)
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3.5 Physical Restraint of Animals (PDF)
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3.6 Aseptic Technique (PDF)
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3.7 Collection of Biological Samples (PDF)
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3.9 Animal Facility Biosecurity (PDF)
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3.10 Requirements for Social Housing of Animals (PDF)
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3.12 Animal Procurement (PDF)
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3.13 The Transportation of Animals (PDF)
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3.14 The Use Dead Vertebrate Animals (PDF)
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3.16 Research Involving Wildlife (PDF)
Species Specific
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4.1 The Use of Zebrafish (PDF)
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4.2 Tumor Inoculation in Rodents (PDF)
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4.3 The Use of the Mouse Ascites Model for Monoclonal Antibody Production (PDF)
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4.4 The Use of Avian Embryos (PDF)
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4.5 Mouse Toe Clipping (PDF)
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4.6 Fish Health Surveillance Program (PDF)
Regulatory Guidance
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AVMA Guidelines for the Euthanasia of Animals: 2020 Edition (PDF)
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Guide For The Care and Use of Agriculture Animals In Research and Teaching (4th Edition) (PDF)
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Occupational Health and Safety in the Care and Use of Research Animals
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USDA Animal and Plant Health Inspection Animal Care Policy Manual
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NIH - How to Write an Application Involving Research Animals
Research Guidelines
Literature Search Strategies
Statistical Significance
IACUC related Research Division Policies
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Responsibilities and Authority of the Attending Veterinarian - University Veterinarian (PDF)
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Responsibilities and Authority of the Institutional Animal Care and Use Committee (IACUC) (PDF)
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Assignment of Principal Investigator/Project Director Role (PDF)
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Variance Form (DOC)
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Housing Animals off Campus/Facility Management Changes (PDF)
Read Clemson University President Jim Barker's directive entitled Statement of Responsibilities for Institution-Wide Compliance with Federal Regulations and Institutional Polices in the Conduct of Teaching and Research Activities Involving Animals (PDF).
ByLaws
IACUC ByLaws (PDF): These regulations govern how committee members are selected, enacts institutional-specific rules, and provides the basic structure for how the committee operates at Clemson University.
